The Discovery of Discrete Developmental Pathways Directing Constitutive and Induced Mast Cells in Mice
J Immunol. 2021 Jul 15;207(2):359-361. doi: 10.4049/jimmunol.2100432. NO ABSTRACT PMID:34644258 | DOI:10.4049/jimmunol.2100432
Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6
J Immunol. 2013 Feb 15;190(4):1758-66. doi: 10.4049/jimmunol.1202567. Epub 2013 Jan 14. ABSTRACT Mast cells (MC) and basophils share expression of the high-affinity receptor for IgE
Secretory phospholipases A2 activate selective functions in human eosinophils
J Immunol. 2003 Mar 15;170(6):3279-88. doi: 10.4049/jimmunol.170.6.3279. ABSTRACT Secretory phospholipases A(2) (sPLA(2)s) are released in large amounts in the blood of patients with systemic inflammatory
Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation
J Immunol. 2013 Jun 15;190(12):5927-38. doi: 10.4049/jimmunol.1203202. Epub 2013 May 6. ABSTRACT We reported that Pla2g5-null mice lacking group V secretory phospholipase A2 (gV-sPLA2) showed
Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma
J Immunol. 2014 Nov 15;193(10):4783-4789. doi: 10.4049/jimmunol.1302947. Epub 2014 Oct 15. ABSTRACT Allergic asthma is a complex disease with a strong genetic component where mast
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,