Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial
JAMA. 2021 Sep 21;326(11):1013-1023. doi: 10.1001/jama.2021.13374. ABSTRACT IMPORTANCE: In patients who require mechanical ventilation for acute hypoxemic respiratory failure, further reduction in tidal volumes, compared
Allergic inflammatory memory in human respiratory epithelial progenitor cells
Nature. 2018 Aug;560(7720):649-654. doi: 10.1038/s41586-018-0449-8. Epub 2018 Aug 22. ABSTRACT Barrier tissue dysfunction is a fundamental feature of chronic human inflammatory diseases1. Specialized subsets of
Global processing provides malignancy evidence complementary to the information captured by humans or machines following detailed mammogram inspection
Sci Rep. 2021 Oct 11;11(1):20122. doi: 10.1038/s41598-021-99582-5. ABSTRACT The information captured by the gist signal, which refers to radiologists’ first impression arising from an initial
Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice
Sci Rep. 2020 Oct 28;10(1):18443. doi: 10.1038/s41598-020-75601-9. ABSTRACT Riboflavin transporter 3 (RFVT3), encoded by the SLC52A3 gene, is important for riboflavin homeostasis in the small
Analysis of anticholinergic adverse effects using two large databases: The US Food and Drug Administration Adverse Event Reporting System database and the Japanese Adverse Drug Event Report database
PLoS One. 2021 Dec 2;16(12):e0260980. doi: 10.1371/journal.pone.0260980. eCollection 2021. ABSTRACT INTRODUCTION: Anticholinergic adverse effects (AEs) are a problem for elderly people. This study aimed to
Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,