Efficacy and safety of dupilumab in patients with uncontrolled severe CRSwNP and a clinical diagnosis of NSAID-ERD: Results from two randomized placebo-controlled phase 3 trials
Allergy. 2021 Aug 30. doi: 10.1111/all.15067. Online ahead of print. ABSTRACT BACKGROUND: About one-tenth of patients with difficult-to-treat chronic rhinosinusitis with nasal polyps (CRSwNP) have
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6
J Immunol. 2013 Feb 15;190(4):1758-66. doi: 10.4049/jimmunol.1202567. Epub 2013 Jan 14. ABSTRACT Mast cells (MC) and basophils share expression of the high-affinity receptor for IgE
Analysis of anticholinergic adverse effects using two large databases: The US Food and Drug Administration Adverse Event Reporting System database and the Japanese Adverse Drug Event Report database
PLoS One. 2021 Dec 2;16(12):e0260980. doi: 10.1371/journal.pone.0260980. eCollection 2021. ABSTRACT INTRODUCTION: Anticholinergic adverse effects (AEs) are a problem for elderly people. This study aimed to
Mouse mast cell protease-6 and MHC are involved in the development of experimental asthma
J Immunol. 2014 Nov 15;193(10):4783-4789. doi: 10.4049/jimmunol.1302947. Epub 2014 Oct 15. ABSTRACT Allergic asthma is a complex disease with a strong genetic component where mast
Global processing provides malignancy evidence complementary to the information captured by humans or machines following detailed mammogram inspection
Sci Rep. 2021 Oct 11;11(1):20122. doi: 10.1038/s41598-021-99582-5. ABSTRACT The information captured by the gist signal, which refers to radiologists’ first impression arising from an initial