GPR17 is a negative regulator of the cysteinyl leukotriene 1 receptor response to leukotriene D4
Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11685-90. doi: 10.1073/pnas.0905364106. Epub 2009 Jun 26. ABSTRACT The cysteinyl leukotrienes (cys-LTs) are proinflammatory lipid mediators
Secretory phospholipases A2 activate selective functions in human eosinophils
J Immunol. 2003 Mar 15;170(6):3279-88. doi: 10.4049/jimmunol.170.6.3279. ABSTRACT Secretory phospholipases A(2) (sPLA(2)s) are released in large amounts in the blood of patients with systemic inflammatory
Mast cells recruited to mesenteric lymph nodes during helminth infection remain hypogranular and produce IL-4 and IL-6
J Immunol. 2013 Feb 15;190(4):1758-66. doi: 10.4049/jimmunol.1202567. Epub 2013 Jan 14. ABSTRACT Mast cells (MC) and basophils share expression of the high-affinity receptor for IgE
Identification of pathophysiological patterns for triage and respiratory support in COVID-19
Lancet Respir Med. 2020 Aug;8(8):752-754. doi: 10.1016/S2213-2600(20)30279-4. Epub 2020 Jun 26. NO ABSTRACT PMID:32598907 | PMC:PMC7319638 | DOI:10.1016/S2213-2600(20)30279-4
Asthma Exacerbations in Patients with Type 2 Diabetes and Asthma on Glucagon-like Peptide-1 Receptor Agonists
Am J Respir Crit Care Med. 2021 Apr 1;203(7):831-840. doi: 10.1164/rccm.202004-0993OC. ABSTRACT Rationale: GLP-1R (glucagon-like peptide-1 receptor) agonists are approved to treat type 2 diabetes
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis
Cell Stem Cell. 2021 Apr 1;28(4):637-652.e8. doi: 10.1016/j.stem.2020.11.004. Epub 2020 Dec 9. ABSTRACT Functional contributions of individual cellular components of the bone-marrow microenvironment to myelofibrosis