Type 2 Cysteinyl Leukotriene Receptors Drive IL-33-Dependent Type 2 Immunopathology and Aspirin Sensitivity
J Immunol. 2018 Feb 1;200(3):915-927. doi: 10.4049/jimmunol.1700603. Epub 2017 Dec 27. ABSTRACT Cysteinyl leukotrienes (cysLTs) facilitate mucosal type 2 immunopathology by incompletely understood mechanisms. Aspirin-exacerbated
Effect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial
JAMA. 2021 Sep 21;326(11):1013-1023. doi: 10.1001/jama.2021.13374. ABSTRACT IMPORTANCE: In patients who require mechanical ventilation for acute hypoxemic respiratory failure, further reduction in tidal volumes, compared
Wiping Away Cellulitis: A Case of Factitious Disorder
Cutis. 2021 Jun;107(6):E29-E30. doi: 10.12788/cutis.0300. NO ABSTRACT PMID:34314328 | DOI:10.12788/cutis.0300
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
Cell Stem Cell. 2021 Dec 25:S1934-5909(21)00520-8. doi: 10.1016/j.stem.2021.12.010. Online ahead of print. ABSTRACT Kidney failure is frequently observed during and after COVID-19, but it remains
The cysteinyl leukotriene 3 receptor regulates expansion of IL-25-producing airway brush cells leading to type 2 inflammation
Sci Immunol. 2018 Oct 5;3(28):eaat9453. doi: 10.1126/sciimmunol.aat9453. ABSTRACT Respiratory epithelial cells (EpCs) orchestrate airway mucosal inflammation in response to diverse environmental stimuli, but how distinct
KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma
N Engl J Med. 2017 May 18;376(20):1911-1920. doi: 10.1056/NEJMoa1613125. ABSTRACT BACKGROUND: Mast cells are present in the airways of patients who have severe asthma despite