Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation
Sci Immunol. 2021 Feb 26;6(56):eabb7221. doi: 10.1126/sciimmunol.abb7221. ABSTRACT Mast cells (MCs) play a pathobiologic role in type 2 (T2) allergic inflammatory diseases of the airway,
KIT Inhibition by Imatinib in Patients with Severe Refractory Asthma
N Engl J Med. 2017 May 18;376(20):1911-1920. doi: 10.1056/NEJMoa1613125. ABSTRACT BACKGROUND: Mast cells are present in the airways of patients who have severe asthma despite
Leukotriene E4 elicits respiratory epithelial cell mucin release through the G-protein-coupled receptor, GPR99
Proc Natl Acad Sci U S A. 2016 May 31;113(22):6242-7. doi: 10.1073/pnas.1605957113. Epub 2016 May 16. ABSTRACT Cysteinyl leukotrienes (cysLTs), leukotriene C4 (LTC4), LTD4, and
Secretory phospholipases A2 induce cytokine release from blood and synovial fluid monocytes
Eur J Immunol. 2002 Jan;32(1):67-76. doi: 10.1002/1521-4141(200201)32:13.0.CO;2-3. ABSTRACT Secretory phospholipases A2 (sPLA2) are released in the blood of patients with various inflammatory diseases and exert
Free propagation phase-contrast breast CT provides higher image quality than cone-beam breast-CT at low radiation doses: a feasibility study on human mastectomies
Sci Rep. 2019 Sep 24;9(1):13762. doi: 10.1038/s41598-019-50075-6. ABSTRACT In this study we demonstrate the first direct comparison between synchrotron x-ray propagation-based CT (PB-CT) and cone-beam
A stomata classification and detection system in microscope images of maize cultivars
PLoS One. 2021 Oct 25;16(10):e0258679. doi: 10.1371/journal.pone.0258679. eCollection 2021. ABSTRACT Plant stomata are essential structures (pores) that control the exchange of gases between plant leaves